I cannot get my mil to take any of her meds, tried crushing them up and putting them in food, she refuses to eat. she has been up for 24 hours.

Is she frightened, aggressive or paranoid? I'd call her doctor and tell him or her about her sypmtoms.

Dissolving in coffee?

What is her behavior like?

Is there someone she trusts or gets along with the best? Have that person work on getting the most important meds in her...hopefully she's on an anti-psychotic...that's the one that will help her be more compliant, less combative and if you can get it in her will increase the chance of her taking the rest of her medication.

Does she have a good neurologist? Call and update him/her...I've heard that Seroquel comes in a dissolvable form maybe the medication your MIL takes does too...She may need her meds adjusted while she gets used to her new enviroment.

Just a couple of suggestions...I hope things get better.

Talk to her doctor and/or pharmacist. Some meds can be made into creams, some can be made into suppositories. If you use the find function (the purple box), you can see other information on this topic.
Good luck to you.

Brian, is she on any anti-psychotic or antidepressant meds?

Or just cognitive meds (Aricept, Namenda, Exelon) and/or meds for other health conditions like high blood pressure?

Call her doctor. That is the only thing you can do. Once they refuse to eat, it really doesn't matter what you put them in they just will refuse to take anything. The only way to get them back on track is to do it inpatient which requires doctors orders.
God bless you for what you are doing.